Low Vitamin D Levels Common in Painful Diabetic Neuropathy
BOSTON — Painful diabetic peripheral neuropathy is associated with significantly reduced vitamin D levels, independent of sunlight exposure, a new study finds.
The study, presented here at the American Diabetes Association (ADA) 2015 Scientific Sessions, suggests a possible role of vitamin D in the pathogenesis of painful diabetic peripheral neuropathy and therefore a potential role of supplementation in its treatment, pending the results of randomized clinical trials, study author Dinesh Selvarajah, MD, of the University of Sheffield, United Kingdom, told Medscape Medical News.
Previous studies demonstrating a link between low vitamin D and neuropathy have not accounted for seasonal differences in vitamin D nor for activity variations that affect vitamin D exposure. This is the first study to carefully control for those factors, Dr Selvarajah noted.
"We've certainly got a smoking gun. We've got a proof of concept. Now we need to do an intervention study to show whether this is a significant finding, because if it is, it's a simple enough treatment," he said.
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